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Light‐Harvesting Photosensitizers for Photodynamic Inactivation of Bacteria under Both Visible and Near‐Infrared Excitations
Authors:Dr Bo Hu  Dr Xian Cao  Ms Tevhide Ozkaya Ahmadov  Dr Rui Ding  Dr Hong Tang  Dr Peng Zhang
Institution:1. Department of Chemistry, University of Cincinnati, Cincinnati, OH, USA;2. School of Life Science and Technology, Xidian University, Xi'an, Shaanxi, China;3. Drug Discovery Center, University of Cincinnati, Cincinnati, OH, USA
Abstract:We report a hybrid singlet oxygen production system, where strong resonance coupling between plasmonic nanoparticles and photosensitizing molecules results in exceptionally high singlet oxygen production under both visible light and near‐infrared light excitation, even for the photosensitizing molecules without near‐infrared absorption. The light‐harvesting property of the plasmon‐photosensitizer hybrids leads to an enhanced, broad‐spectrum photodynamic inactivation of bacteria under a wide range of excitations, including that with near‐infrared light.
Keywords:light-harvesting  photodynamic inactivation  riboflavin  silver nanoparticles  singlet oxygen
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