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Total Synthesis of Ouabagenin and Ouabain |
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| Authors: | Maddi&#x;Sridhar Reddy Hongxing Zhang Serge Phoenix Pierre Deslongchamps |
| Institution: | Maddi Sridhar Reddy,Hongxing Zhang,Serge Phoenix,Pierre Deslongchamps |
| Abstract: | All done! A full account of the total synthesis of ouabagenin and ouabain has been described. The synthesis was achieved through a polyanionic cyclization strategy. Degradation studies provide an ultimate proof for a key intermediate observed in the synthesis.  |
| Keywords: | cycloaddition glycosides glycosylation steroids total synthesis |