Biological activity of new amino phospha betaines with C10–C18 alkyl groups |
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| Institution: | 1. A. M. Butlerov Institute of Chemistry, Kazan Federal University, 420008 Kazan, Russian Federation;2. Kazan State Medical University, 420012 Kazan, Russian Federation |
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| Abstract: | New amino phospha betaines were obtained by quaternization of potassium salt of amino phosphonate and higher alkyl bromides. The structure of isopropyl (N-dodecyl-N,N- dimethylammoniomethyl)phosphonate was confirmed by single crystal X-ray diffraction. All synthesized compounds demonstrate high antibacterial and antifungal activities. |
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| Keywords: | betaines organophosphorus compounds quaternary ammonium salts amino phosphonates antimicrobial activity antifungal activity X-ray diffraction |
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