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Synthesis and inverse virtual screening of new bi-cyclic structures towards cancer-relevant cellular targets |
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| Authors: | Crocetti Letizia Floresta Giuseppe Nazir Shabnam Vergelli Claudia Bhogal Amrit Biancalani Claudio Cesari Nicoletta Giovannoni Maria Paola Cilibrizzi Agostino |
| Institution: | 1.Department of NEUROFARBA, University of Florence, Via Ugo Schiff 6, Sesto Fiorentino, FI, 50019, Italy ;2.Institute of Pharmaceutical Science, King’s College London, Stamford Street, London, SE1 9NH, UK ;3.Department of Analytical, Environmental and Forensic Sciences, King’s College London, 150 Stamford Street, London, SE1 9NH, UK ; |
| Abstract: | Structural Chemistry - We report here synthetic approaches to access new classes of small molecules based on three heterocyclic scaffolds, i.e. 3,7-dihydropyrimido4,5-d]pyridazine-4,8-dione,... |
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