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| First Total Synthesis of Cleroindicin B,(±) Cleroindicin C and E | |
| 作者姓名： | Jin CHEN Jun TIAN* Feng E WU Norio Kawabe Masahiko Tokuda Laboratory of Natural Materia Medica Chengdu Institute of Biology the Chinese Academy of Sciences Chengdu Basic Research Laboratories Toray Industries Inc. Tebiro |
| 作者单位： | Jin CHEN1，Jun TIAN1*，Feng E WU1，Norio Kawabe2，Masahiko Tokuda2 1Laboratory of Natural Materia Medica，Chengdu Institute of Biology，the Chinese Academy of Sciences，Chengdu 610041 2Basic Research Laboratories，Toray Industries，Inc.，Tebiro 1111 |
| 摘 要： | The isolation of cleroindicins B, C and cleroindicin E, together with three novel related compounds cleroindicins A, D and F, from chinese folk medicine Clerodendrum indicum Linn. was reported before1. Pharmaceutical studies showed that cleroindicin C has certain anticancer activity, so its total synthesis attracted our considerable interest.Cleroindicin B Cleroindicin C Cleroindicin EThe commercially available 2-(p-methoxyphenyl) ethanol 1 was selected as the starting material. Compound… |
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