A novel alkaloid from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang |
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| Authors: | Chao Liu Fen Zhao RuoYun Chen |
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| Institution: | Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beijing 100050, China |
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| Abstract: | A new alkaloid, sinensine (1), had been isolated from the fruiting bodies of Ganoderma sinense Zhao, Xu et Zhang. Its structure was elucidated on the basis of 1D and 2D spectral analysis. This alkaloid exhibited activity in protecting the injury induced by hydrogen peroxide oxidation on HUVEC, with EC50 value 6.2 μmol/L. |
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| Keywords: | Alkaloid Ganoderma sinense Sinensine |
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