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Demethoxylation and O-Demethylation of Pseudaconine and Isotalatizidine
作者姓名:Ju Zheng FAN  Zheng Bang LI  Qiao Hong CHEN Feng Peng WANGi  Bo Gang LI
作者单位:Department of Chemistry of Medicinal Natural Products,School of Pharmacy,West China University of Medical Sciences,Chengdu 610041 Chengdu Institute of Biology,Chinese Academy of Sc
基金项目:We thank the National Natural Science Foundation of China! (No. 393707),the Chengdu Diao Pharmaceutical Company for support o
摘    要:Thenorditerpenoidalkaloidsnotonlyhaveimportantpharmacologicalactivities,butalsomaysetoffalotofinterestingchemicalreactionsl'2.Inthecourseofourstudiesonsearchforhighactivity,lowtoxicitycompoundsandconversionoftheskeletons,aseriesofmodificationsofthesealkaloidshavebeenreported'.Inthepresentpaper,wereportsomechemicalreactionsincludingthedemethoxylation,O-demethylationandoxidation,ofthenorditerpenoidalkaloidspseudaconine1andisotalatizidine7.Treatmentofthenorditerpenoidalkaloidscontainingmethoxylgr…


Demethoxylation and O-Demethylation of Pseudaconine and Isotalatizidine
Ju Zheng FAN,Zheng Bang LI, Qiao Hong CHEN Feng Peng WANGi,Bo Gang LI.Demethoxylation and O-Demethylation of Pseudaconine and Isotalatizidine[J].Chinese Chemical Letters,2000,41(5).
Authors:Ju Zheng FAN  Zheng Bang LI  Qiao Hong CHEN  Feng Peng WANG  Bo Gang LI
Abstract:Demethoxylation and O-demethylation of the norditerpenoid alkaloids pseudaconine and isolatatizidine were described.
Keywords:Norditerpenoid alkaloid  demethoxylation  O-demethylation  oxidation  pscudaconinc  isotalatizidine  
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