Optical monitoring the degradation of PLGA inverse opal film |
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| Authors: | Li-Guo Sun Zhuo-Ying Xie Yuan-Jin Zhao Hong-Mei Wei Zhong-Ze Gu |
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| Institution: | 1. State Key Laboratory of Bioelectronics, Southeast University, Nanjing 210096, China ;School of Chemistry and Materials, Heilongjiang University, Harbin 150080, China
2. State Key Laboratory of Bioelectronics, Southeast University, Nanjing 210096, China |
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| Abstract: | Implantable materials have broad applications in tissue engineering and in vivo sensors. It is essential to know the detailed information of the implantable materials during their degradation. In this paper, we developed a method to monitor the degradation process of a well-used biomaterial, poly(lactide-co-glycolide) (PLGA) by taking advantage of inverse opal structure. We found that mass loss, molecular weight and glass transition temperature of PLGA during the degradation process in Hank's artificial body fluid can be in situ monitored by measuring the optical properties of PLGA inverse opal. |
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| Keywords: | PLGA inverse opal Degradation Optical monitoring |
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