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Synthesis and bioactivity of novel coumarin derivatives containing(E)-methyl 2-(methoxyimino)-2-phenylacetates
Authors:Ai Ying Guan  Chang Ling Liu  Zhi Nian Li  Ming Xing Zhang State Key Laboratory of the Discovery  Development of Novel Pesticide  Shenyang Research Institute of Chemical Industry CoLtd  Shenyang  China
Institution:State Key Laboratory of the Discovery and Development of Novel Pesticide, Shenyang Research Institute of Chemical Industry Co.Ltd., Shenyang 110021, China
Abstract:Ten coumarin derivatives containing(E)-methyl 2-(methoxyimino)-2-phenylacetate were synthesized and bioassayed.The compounds were identified by IR,~1H NMR and elemental analyses.The test results indicated that compound 5j(R~1 is methyl and R~2 is n-C_6H_(13)) was the optimal structure in this paper with good fungicidal activity against CDM(85%) at 6.25 mg/L concentration.
Keywords:Coumarins  Methoxyacrylates  Intermediate derivatization method  Fungicides  
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