| Combination of Micro-fluidic Chip with Fluorescence Correlation Spectroscopy for Single Molecule Detection |
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| 作者姓名： | Rui BI Pu Dun ZHANG Chao Qing DONG Ji Cun REN |
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| 作者单位： | College of Chemistry ＆ Chemical Engineering, Shanghai Jiaotong University, Shanghai 200240 |
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| 摘 要： | A single molecule detection technique was developed by the combination of a single channel poly (dimethylsiloxane)/glass micro-fluidic chip and fluorescence correlation spectroscopy (FCS). This method was successfully used to determine the proportion of two model components in the mixture containing fluorescein and the rhodamine-green succinimidyl ester.
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| 关 键 词： | 荧光关联能谱法 微射流芯片 单分子检测 玫瑰精 |
| 收稿时间： | 2005-10-08 |
Combination of Micro-fluidic Chip with Fluorescence Correlation Spectroscopy for Single Molecule Detection |
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| Rui BI Pu Dun ZHANG Chao Qing DONG Ji Cun REN.Combination of Micro-fluidic Chip with Fluorescence Correlation Spectroscopy for Single Molecule Detection[J].Chinese Chemical Letters,2006,17(4):521-524. |
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| Authors: | Rui BI Pu Dun ZHANG Chao Qing DONG Ji Cun REN |
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| Abstract: | A single molecule detection technique was developed by the combination of a single channel poly (dimethylsiloxane)/glass micro-fluidic chip and fluorescence correlation spectroscopy (FCS). This method was successfully used to determine the proportion of two model components in the mixture containing fluorescein and the rhodamine-green succinimidyl ester. |
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| Keywords: | Fluorescence correlation spectroscopy micro-fluidic chip single molecule detection |
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