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Synthesis of an optically active intermediate for A-ring of 19-nor- 1α,25-dihydroxyvitamin D3
作者姓名:Shan  Qian  Li  Hai  Lei  Tang  Jin  Cheng  Yang  Yong  Wu
作者单位:Shan Qian,Li Hai,Lei Tang,Jin Cheng Yang,Yong Wu *Key Laboratory of Drug Targeting and Novel Drug Delivery Systems,West China School of Pharmacy,Sichuan University,Chengdu 610041,China
基金项目:Acknowledgment Financial support from the National Natural Science Foundation of China (No. 29972013) is gratefully acknowledged.
摘    要:An optically active intermediate 5 for A-ring of 19-nor-1a,25-dihydroxyvitamin D3 2 has been synthesized in five steps, starting from readily available, inexpensive D( )-xylose 6 with good yield.

关 键 词:19-去甲-1α  25-二羟维生素D3  A环  光学活性中间体  合成
收稿时间:2006-10-10

Synthesis of an optically active intermediate for A-ring of 19-nor-1α,25-dihydroxyvitamin D3
Shan Qian Li Hai Lei Tang Jin Cheng Yang Yong Wu.Synthesis of an optically active intermediate for A-ring of 19-nor-1α,25-dihydroxyvitamin D3[J].Chinese Chemical Letters,2007,18(3):261-262.
Authors:Shan Qian  Li Hai  Lei Tang  Jin Cheng Yang  Yong Wu  
Institution:Key Laboratory of Drug Targeting and Novel Drug Delivery Systems, West China School of Pharmacy, Sichuan University, Chengdu 610041, China
Abstract:An optically active intermediate 5 for A-ring of 19-nor-1a,25-dihydroxyvitamin D3 2 has been synthesized in five steps, starting from readily available, inexpensive D( )-xylose 6 with good yield.
Keywords:A-ring of 19-nor-1a  25-dihydroxyvitamin D3  Intermediate  Synthesis
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