One-pot synthesis of 7-bromo-1-[4-(1-cyano-1-methylethyl)]-phenyl-[1,2,4]-triazole-[4,3-a]-quinoxalin |
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| Authors: | Yan Yang Hong Gang Hu Qing Jie Zhao Shi Chong Yu Zhi Gang Dan Yan Zou Qiu Ye Wu |
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| Institution: | Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China |
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| Abstract: | 1,2,4]-Triazole-4,3-a]-quinoxaline is an important component of many drugs. The yield of the reported methods for triazole cyclization step was usually as low as 20%. In this article, the triazole cyclization step was successfully done by using microwave method with a high yield of 75% for the first time. |
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| Keywords: | [1 2 4]-Triazole-[4 3-a]-quinoxaline Microwave Synthesis |
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