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Palladium-catalyzed direct coupling reaction of propargylic alcohols with arylboronic acids
Authors:Masahiro Yoshida
Institution:Department of Organic Chemistry, Graduate School of Pharmaceutical Sciences, Tohoku University, Aobayama, Sendai 980-8578, Japan
Abstract:The direct coupling of propargylic alcohols with arylboronic acids has been achieved using palladium catalyst. Various propargylic alcohols and arylboronic acids can be coupled to afford the corresponding allenic and propargylic arenes, which are selectively produced depending on the substituent on the propargylic alcohol, respectively.
Keywords:Palladium  Coupling reactions  Boronic acids  Propargylic compounds
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