|
|||||
|
|
An enantioselective Michael addition of malonate to nitroalkenes catalyzed by low loading demethylquinine salts in water |
|
| Authors: | Fu-Xin Chen Quan Wang Dong-Yan Zhang Rui Wang |
| Institution: | a Institute of Biochemistry and Molecular Biology, School of Life Sciences, and State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China b State Key Laboratory for Oxo Synthesis and Selective Oxidation, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou, Gansu 730000, China |
| Abstract: | An enantioselective Michael addition of malonate to nitroalkenes is efficiently catalyzed by low loading demethylquinine salts in water; the yield range from 49% to 93% and the ee up to 90%. |
| Keywords: | Organocatalysis Michael addition Salt catalysis Nitroalkenes Water |
| 本文献已被 ScienceDirect 等数据库收录！ | |