Synthesis of 2-amino-2,4-anhydro-3-O-(2-tetrahydropyranyl)-psicofuranose: a versatile intermediate for S-type locked nucleosides |
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Authors: | Chamakura VNS Varaprasad Kanda S Ramasamy Zhi Hong |
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Institution: | Drug Discovery, Valeant Pharmaceutical Research and Development, 3300 Hyland Avenue, Costa Mesa, CA 92614, USA |
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Abstract: | 2-Amino-2,4-anhydro-psicofuranose derivative was synthesized starting from d-fructose. |
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Keywords: | Locked nucleosides Bicyclic sugars |
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