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Resolution of N-benzyl-N-(1,2-dihydro-2-oxoquinolin-1-yl)glycine
Authors:Robert S Atkinson  Brian D Judkins
Institution:Department of Chemistry, University of Leicester, Leicester LE1 7RH UK
Abstract:The NN chiral axis in the title glycine derivative has allowed its resolution into enantiomers: the barrier Δ G for racemisation (rotation around the NN bond) is 26.2 Kcal mol?1.
Keywords:
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