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Efficient N-arylation of pyridazin-3(2H)-ones |
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| Authors: | Jeum-Jong Kim Su-Dong Cho Hyun A Chung JR Falck |
| Institution: | a Department of Chemistry and Environmental Biotechnology, National Core Research Center, Gyeongsang National University, Chinju 660-701, Korea b Department of Chemistry and Research Institute of Basic Science, Changwon National University, Changwon 641-773, Korea c Department of Chemistry and Research Institute of Life Science, Gyeongsang National University, Chinju 660-701, Korea d Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA |
| Abstract: | A variety of substituted pyridazin-3(2H)-ones are directly N-arylated in good yield using lead tetraacetate/zinc chloride in benzene or in substituted benzenes including chloro- and bromobenzene. |
| Keywords: | N-Arylation Pyridazin-3(2H)-ones Lead tetraacetate Zinc chloride |
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