Catalytic asymmetric intramolecular hydroamination of aminoalkenes |
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| Authors: | Tokutaro Ogata |
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| Institution: | Graduate School of Pharmaceutical Sciences, Kyoto University, Yoshida, Sakyo-ku, Kyoto 606-8501, Japan |
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| Abstract: | Asymmetric intramolecular cyclization of aminoalkenes was catalyzed by a catalytic amount of n-butyllithium, diisopropylamine, and a newly designed chiral bisoxazoline in toluene to produce kinetically controlled exo-cyclized amines with up to 91% ee quantitatively. |
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