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Sequential regio and chemoselective cross-coupling reactions by means of O-tri-isopropylsulfonate of 4-bromo-pyridazine 3,6-dione |
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| Authors: | João X de Araújo-Júnior Martine Schmitt Pascal Benderitter |
| Institution: | a Institut Gilbert Laustriat, UMR 7175, Faculté de Pharmacie, 74 route du Rhin, BP 60024, 67401 Illkirch, France b Escola de Enfermagem e Farmacia, Deptode Química, Universidade Federalde Alagoas, cidade Universitaria, 57.072-970, Maceió-AL, Brazil |
| Abstract: | Regioselective desymmetrization of 4-substituted pyridazin-3,6-diones using sterically hindered 2,4,6-triisopropylphenyl-sulfonylchloride allowed efficient sequential palladium cross-coupling reactions. |
| Keywords: | 4-Bromo-pyridazine-3 6-dione 3 6-Dichloropyridazines Amination Palladium cross-coupling reaction Microwave heating Suzuki reaction |
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