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A new synthesis of flavonoids via Heck reaction
Authors:Armandodoriano BiancoClaudia Cavarischia  Angela FarinaMarcella Guiso  Carolina Marra
Institution:Dipartimento di Chimica Università ‘La Sapienza’, Istituto di Chimica Biomolecolare del CNR, Piazzale Aldo Moro 5, I-00185 Roma, Italy
Abstract:Several naturally occurring flavonoids have been synthesised following a new proposed method based on the use of the Heck reaction. The key step involves the coupling of an aryl vinyl ketone with an aryl iodide. This procedure affords the flavonoid moiety in a single step.
Keywords:Heck reaction  flavonoids  palladium
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