An efficient method for the conversion of aromatic and aliphatic nitriles to the corresponding N-tert-butyl amides: a modified Ritter reaction |
| |
| Authors: | KLaxma Reddy |
| |
| Institution: | Process Research and Development, Bristol-Myers Squibb Pharmaceutical Research Institute, 5 Research Parkway, Wallingford, CT 06492-7660, USA |
| |
| Abstract: | Aromatic and aliphatic nitriles react with tert-butyl acetate in the presence of a catalytic amount of sulfuric acid to give the corresponding N-tert-butyl amides in excellent yields. |
| |
| Keywords: | modified Ritter reaction nitriles tert-butyl acetate N-tert-butyl amides |
| 本文献已被 ScienceDirect 等数据库收录！ |
