A novel greener glycosidation using an acid-ionic liquid containing a protic acid |
| |
| Authors: | Kaname SasakiHideyuki Nagai Shuichi MatsumuraKazunobu Toshima |
| |
| Institution: | Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan |
| |
| Abstract: | The glycosidations of glucopyranosyl diethyl phosphite and alcohols using an ionic liquid, 1-n-hexyl-3-methylimidazolium trifluoromethanesulfonimidide (C6mimNTf2]) containing a protic acid, trifluoromethanesulfonimide (HNTf2), as a novel solvent-catalyst system, effectively proceeded under mild conditions to give the corresponding glycosides in good to high yields. Furthermore, this acid-ionic liquid combination could be reused many times for the glycosidations without any loss in efficiency. |
| |
| Keywords: | glycosidation ionic liquid protic acid diethyl phosphite green chemistry |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
