Dielectric studies of molecular complexes ofDDT with some compounds of biological interest

The molecular complexation ofDDT (acceptor) with some compounds of biological interest as donors (e.g. indole, 2-methylindole, 3-methylindole, benzene and naphthalene) have been studied using refractive index,Guggenheim and dielectric titration plot methods. The interaction between these donors with solvents (CCl₄ and C₆H₆) have also been observed by calculating _ind through _ind=_sol–_inert. These data have shown that the molecular interaction between polar solutes and non-polar aromatics is governed by dipole-induced dipole electrostatic attraction. The dipole moment obtained due to charge transfer (_DA) has also been calculated and found that its value increases with the increase in the extent of interaction between donor and acceptor. These data support the charge-transfer complex formation hypothesis for the mode of action ofDDT on molecular level.

---

Dielektrizitäts-Untersuchungen an Molekülkomplexen von DDT mit einigen biologisch relevanten Verbindungen

Zusammenfassung Es wurden Molekülkomplexe vonDDT (als Acceptor) mit einigen Verbindungen von biologischem Interesse (als Donoren: Indol, 2-Methyl-indol, 3-Methyl-indol, Benzol und Naphthalin) mittels Brechungsindex,Guggenheim-Methode und dielektrischer Titration untersucht. Dipolmomentberechnungen ergaben, daß die intermolekulare Wechselwirkung von einer Anziehung induzierter Dipol-Dipol bestimmt wird; es wurde auch der charge-transfer-Anteil des Dipolmoments abgeschätzt. Alle diese Daten unterstützen die Annahme der charge-transfer-Komplexierung vonDDT.