| 芳基肟胺菊酯类化合物和1，2，4－噁二唑衍生物的合成及其生物活性研究 |
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| 引用本文： | 金桂玉,赵国锋,郑健禺.芳基肟胺菊酯类化合物和1，2，4－噁二唑衍生物的合成及其生物活性研究[J].高等学校化学学报,1994(7). |
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| 作者姓名： | 金桂玉 赵国锋 郑健禺 |
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| 作者单位： | 南开大学元素有机化学研究所 |
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| 摘 要： | 芳基肟胺化合物与取代环丙烷羧酸酰氯在Ｅｔ_３Ｎ作用下室温反应得到芳基肟胺菊酯类化合物，在甲苯中回流反应则得到含取代环丙烷基的１，２，４－ 二唑衍生物。前者在甲苯中回流，ＨＯＡｃ作催化剂时发生环化反应也生成１，２，４－ 二唑衍生物．初步生物活性测试表明这些化合物具有的杀菌和除草活性．
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| 关 键 词： | 芳基肟胺菊酯，1，2，4－ 二唑，环化反应，生物活性 |
Studies on the Synthesis and Biological Activities of Aryl Amidoximyl Chrysanthemumates and 1,2,4-Oxadiazole Derivatives |
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| JIN Gui-Yu,ZHAO Guo-Feng,ZHENG Jian-Yu.Studies on the Synthesis and Biological Activities of Aryl Amidoximyl Chrysanthemumates and 1,2,4-Oxadiazole Derivatives[J].Chemical Research In Chinese Universities,1994(7). |
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| Authors: | JIN Gui-Yu ZHAO Guo-Feng ZHENG Jian-Yu |
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| Abstract: | Aryl amidoximes reacted with substituted cyclopropane carbonyl chlorides under the action of Et_3N in room temperature to give aryl amidoximyl chrysanthemumates and under reflux in toluene to give 1,2,4-oxadiazole derivatives.When the formers reacted under reflux in toluene using HOAc as catalysis,the cyclization took place and 1,2,4-oxadiazole derivatives were also obtained.The preliminary biological tests indicated that these compounds had fungicidal and herbicidal activities. |
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| Keywords: | Aryl amidoximyl chrysanthemumate 1 2 4-Oxadiazole Cyclization reaction Biological activity |
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