中红外光谱无创伤检测血糖新方法

糖尿病是一种常见的代谢内分泌疾病，是由于人体内缺乏胰岛素或其受体异常所致，以高血糖为主要特征，为一种世界范围内的流行疾病，近年来其发病呈显著上升趋势，目前全世界约有10％的成年人身患此病，在我国，糖尿病患者约有四千万人，血糖的测量对于临床诊断和糖尿病人血糖的控制很重要，常规的方法是静脉取血测量血糖，该方法会给病人带来一定的痛苦，同时增加了感染机会，

A Novel Non-invasive Method of Blood Glucose Measurement Using FT-Mid-IR Spectroscopy

The blood glucose concentrations of volunteers from diabetes patients and healthy adults(all patients and volunteer who joined this experiment gave their consents) were measured by using a modified WQF-200 FTIR spectrometer with a newly designed ATR accessory. The results of this method are in good agreement with the clinical blood detection. The determination basis for this technique from the physiological point of view are also discussed based on the experimental results, which indicated that the glucose components measured by the FT-Mid-IR-ATR are from the secretions on the skin and glucose components within the body. The glucose components in both sources exhibit a linear relationship with blood glucose concentration within the body. All the results demonstrated that blood glucose concentration can be measured in a convenient, rapid and non-invasive way using ATR-FTIR spectroscopy, which is suitable for developing of a new technique to monitor the continuous variation of blood glucose concentration of diabetes patients in real time.