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新(4′-三氟甲基嘧啶基)-2-苯磺酰脲衍生物的合成及生物活性
引用本文:王红学,李芳,许丽萍,李永红,王素华,李正名.新(4′-三氟甲基嘧啶基)-2-苯磺酰脲衍生物的合成及生物活性[J].高等学校化学学报,2010,31(1):64-67.
作者姓名:王红学  李芳  许丽萍  李永红  王素华  李正名
作者单位:南开大学农药国家工程研究中心,元素有机化学国家重点实验室,天津,300071
摘    要:以单取代苯磺酰脲除草剂NK92825和NK94827为基础,将三氟甲基引入嘧啶环中,设计合成了17个新的4′-三氟甲基嘧啶苯磺酰脲化合物,产物结构均经1H NMR及元素分析确证.目标化合物经盆栽试验,结果表明,部分化合物有较好的除草活性.

关 键 词:磺酰脲  三氟甲基嘧啶  除草活性
收稿时间:2009-04-09

Synthesis and Biological Activity of New Trifloromethylpyrimidine Phenylsulfonylurea Derivatives
WANG Hong-Xue,LI Fang,XU Li-Ping,LI Yong-Hong,WANG Su-Hua,LI Zheng-Ming.Synthesis and Biological Activity of New Trifloromethylpyrimidine Phenylsulfonylurea Derivatives[J].Chemical Research In Chinese Universities,2010,31(1):64-67.
Authors:WANG Hong-Xue  LI Fang  XU Li-Ping  LI Yong-Hong  WANG Su-Hua  LI Zheng-Ming
Institution:National Pesticide Engineering Research Center;State Key Laboratory of Elemento-Organic Chemistry;Nankai University;Tianjin 300071;China
Abstract:Seventeen new sulfonylurea derivatives with trifloromethyl group in the pyrimidine ring were designed and synthesized,based on NK92825 and NK94827. Their structures were confirmed by 1H NMR and elemental analysis. Preliminary herbicidal activities of these new sulfonylurea compounds were determined by pot bioassay experiments at dosage of 375 g/ha. The results show that some derivatives display good heribicidal activities.
Keywords:Sulfonylurea  Trifloromethyl-pyrimidine  Herbicidal activity  
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