细菌感染成像的研究进展

由致病菌或条件致病菌侵入机体繁殖而产生的毒素和其它代谢产物所引起的感染性疾病是目前全球范围内的主要死亡原因之一. 感染性疾病的早期诊断是对其进行有效治疗与控制的重要途径. 分子影像技术的快速发展给体内细菌感染的评估带来了前所未有的变化和机遇. 本文综合评述了计算机断层扫描、 正电子发射断层扫描、 超声成像、 磁共振成像、 荧光成像及光声成像等成像方式在细菌感染体内成像中的研究进展、 不足和发展方向等, 以期为活体细菌感染检测方法的发展提供参考.

Research Progress of Bacterial Infection Imaging

As one of the major causes for death， bacterial infection is caused by pathogenic bacteria or opportunistic pathogens that invade the human body and proliferate， producing toxins and other metabolites. Early diagnosis of infectious diseases is an important approach to effective treatment and control of infectious diseases. The rapid development of molecular imaging technology has brought unprecedented changes and opportunities to the evaluation of bacterial infection in vivo. This article reviews the research progress and the future development direction of imaging of bacterial infection in vivo based on the imaging methods such as computed tomography， ultrasound imaging， magnetic resonance imaging， fluorescence imaging， photoacoustic imaging， and others， aiming to provide reference for the development of detecting bacterial infection in vivo.