| 血液灌流用胆红素吸附剂的吸附性能研究 |
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| 引用本文： | 袁直,魏斌,何炳林,顾汉卿.血液灌流用胆红素吸附剂的吸附性能研究[J].高等学校化学学报,1999,20(6):903-905. |
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| 作者姓名： | 袁直 魏斌 何炳林 顾汉卿 |
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| 作者单位： | 1. 吸附分离功能高分子材料国家重点实验室, 南开大学高分子化学研究所, 天津 300071;
2. 天津市泌尿外科研究所, 天津 300211 |
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| 基金项目： | 教育部重点科技项目基金,天津市自然科学基金 |
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| 摘 要： | 胆红素是一种内源性毒素.急性肝损伤时,体内胆红素的排泄受到阻碍.如何能有效地排除高浓度的胆红素,引起了各国学者的高度重视1].文献2,3]报道,在血液净化疗法治疗高胆红素血症中,当胆红素吸附剂上含有氨基阳离子时,可以提高其对胆红素的吸附量.
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| 关 键 词： | 高胆红素血症 血液灌流 胆红素吸附剂 |
| 收稿时间： | 1998-08-24 |
Studies on the Adsorption of Bilirubin by Adsorbents |
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| YUAN Zhi,WEI Bin,HE Bing-Lin,GU Han-Qing.Studies on the Adsorption of Bilirubin by Adsorbents[J].Chemical Research In Chinese Universities,1999,20(6):903-905. |
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| Authors: | YUAN Zhi WEI Bin HE Bing-Lin GU Han-Qing |
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| Institution: | 1. The State Key Laboratory of Functional Polymeric Materials for Adsorption Separation, The Institute of Polymer Chemistry, Nankai University, Tianjin, 300071;
2. Tianjin Institute of Urologic Surgery, Tianjin, 300211 |
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| Abstract: | Polymeric adsorbents containing aminogroup for bilirubin were synthesized and the factors affecting the adsorption were also studied. The results show that the adsorption efficiency for bilirubin is over 80% in aqueous phosphate buffer, and 50% in the presence of bovine serum albumin within 2 h. The hemocompatibility of adsorbents is good. So it is hopeful to be used in the hemoperfusion. |
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| Keywords: | Bilirubinemia Hemoperfusion Adsorbent for bilirubin |
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