| 阳虚体质者血清和尿液的核磁共振代谢组学 |
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| 引用本文： | 李英帅,王琦,袁卓珺.阳虚体质者血清和尿液的核磁共振代谢组学[J].高等学校化学学报,2011,32(11):2521-2527. |
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| 作者姓名： | 李英帅 王琦 袁卓珺 |
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| 作者单位： | 北京中医药大学基础医学院,北京,100029 |
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| 基金项目： | 国家自然科学基金(批准号:90709050)资助 |
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| 摘 要： | 采用基于核磁共振(NMR)的代谢组学方法研究了中医阳虚体质及平和体质(正常对照)的血清和尿液,分析了阳虚体质的特征代谢物.实验收集阳虚体质及平和体质各30人的血清及尿液样品,采用多元统计分析方法研究了阳虚质组和对照组血清和尿液中的内源性代谢差异,结果表明,阳虚质血清中乳酸、极低密度脂蛋白/低密度脂蛋白、N-乙酰糖蛋白、...
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| 关 键 词： | 阳虚体质 核磁共振 代谢组学 |
| 收稿时间： | 2010-12-03 |
NMR-based Metabonomics Studies on Serum and Urine of Yang-deficiency Constitution |
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| LI Ying-Shuai,WANG Qi,YUAN Zhuo-Jun.NMR-based Metabonomics Studies on Serum and Urine of Yang-deficiency Constitution[J].Chemical Research In Chinese Universities,2011,32(11):2521-2527. |
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| Authors: | LI Ying-Shuai WANG Qi YUAN Zhuo-Jun |
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| Institution: | LI Ying-Shuai,WANG Qi,YUAN Zhuo-Jun (Basic Medicine College,Beijing University of Chinese Medicine,Beijing 100029,China) |
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| Abstract: | Nuclear magnetic resonance(NMR)-based metabonomics was applied to study the yang-deficiency constitution by analyzing metabolic profiling of serum and urine.The purpose of this study is to determine an array of characteristic metabolites in serum and urine samples from yang-deficiency constitution person and then to interpret these metabolites in possible metabolic pathway.Serum and urine samples from 30 yang-deficiency constitution person with 30 balanced constitution person were collected.Differences in e... |
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| Keywords: | Yang-deficiency constitution Nuclear magnetic resonance(NMR) Metabonomics |
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