| 甘西鼠尾草中三个新的萜类化合物 |
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| 引用本文： | 杨阳,吴志军,杨颖博,来威,孙连娜,陈万生.甘西鼠尾草中三个新的萜类化合物[J].高等学校化学学报,2011,32(6):1318-1322. |
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| 作者姓名： | 杨阳 吴志军 杨颖博 来威 孙连娜 陈万生 |
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| 作者单位： | 杨阳,吴志军,杨颖博,来威,陈万生,YANG Yang,WU Zhi-Jun,YANG Ying-Bo,LAI Wei,CHEN Wan-Sheng(解放军第二军医大学附属长征医院药学部,上海,200003);孙连娜,SUN Lian-Na(解放军第二军医大学药学院,上海,200433) |
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| 基金项目： | 上海科学技术委员会科技专项资金项目 |
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| 摘 要： | 采用反复硅胶、葡聚糖凝胶、反相硅胶及MCI凝胶柱色谱等多种色谱方法分离纯化了甘西鼠尾草的化学成分,根据理化性质和波谱数据对化合物的结构进行了鉴定.由甘西鼠尾草的根和根茎的50%乙醇提取物中得到了2个新的二萜化合物,命名为甘西鼠尾三醇A(1)和甘西鼠尾三醇B(2),同时得到了一个新的单萜苷化合物,命名为甘西鼠尾甲苷(3)...
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| 关 键 词： | 甘西鼠尾草 化学成分 甘西鼠尾三醇 A 甘西鼠尾三醇 B 甘西鼠尾甲苷 |
| 收稿时间： | 2010-07-07 |
Three New Terpenoids from Salvia przewalskii Maxim |
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| YANG Yang,WU Zhi-Jun,YANG Ying-Bo,LAI Wei,SUN Lian-Na,CHEN Wan-Sheng.Three New Terpenoids from Salvia przewalskii Maxim[J].Chemical Research In Chinese Universities,2011,32(6):1318-1322. |
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| Authors: | YANG Yang WU Zhi-Jun YANG Ying-Bo LAI Wei SUN Lian-Na CHEN Wan-Sheng |
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| Institution: | 1. Department of Pharmacy, Changzheng Hospital, Second Military Medical University of PLA, Shanghai 200003, China;
2. School of Pharmacy, Second Military Medical University of PLA, Shanghai 200433, China |
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| Abstract: | Salvia przewalskii Maxim. (Labiatae) is widely distributed in the western areas of China, such as Gansu, Sichuan, Yunnan and Tibet provinces. And it has been used as a substitute in Chinese folk medicine for S. miltiorrhiza Bge. (Dan Shen). The mainly chemical constituents of S. przewalskii are diterpenoids and phenolic acids. In our search, isolation and purification were carried out repeatedly by silica gel, Sephadex LH-20, ODS C18 and MCI gel column chromatography. Two new diterpenoids, named ganxintriol A (1) and ganxintriol B (2), and a new monoterpenoid glycoside, named ganxinoside A (3), were obtained from 50% ethanol extract of the roots and rhizomes of S. przewalskii. Their structures were established on the basis of physical methods, chemical methods and spectral data. |
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| Keywords: | A B |
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