快速pH响应丝胶/聚甲基丙烯酸互穿网络水凝胶的合成及表征

采用同步互穿网络方法制备丝胶蛋白(SS)/聚甲基丙烯酸(PMAA)为组分的互穿网络(IPN)水凝胶. 研究了互穿网络水凝胶对介质pH的刺激响应性能. 结果表明, IPN水凝胶具有强烈的pH刺激响应性能. 在pH=9.2的缓冲溶液中, —COOH解离成 —COO-, 渗透压与网络之间的静电排斥作用导致IPN的溶胀度增大; 当pH减小时, 溶胀度随之减小. IPN水凝胶具有快速退溶胀速率及可逆溶胀-收缩性能.

Synthesis and Characterization of Fast pH-Responsive Silk Sericin/Poly(methacrylic acid) Interpenetrating Polymer Network Hydrogel

Interpenetrating polymer networks(IPN) composed with poly(methacrylic acid)(PMAA) and silk sericin(SS) were prepared by the simultaneous-IPN method. The swelling behavior of the resultant IPN hydrogels was studied at various pH values. The results show that the swelling ratios of the IPNs depend significantly on pH of the aqueous solutions. In pH=9.2, the IPNs have a higher swelling ratio due to the repulsion between —COO- groups derived from —COOH of the polymer chains and the osmosis. However, the swelling ratios diminish with the decrease of pH values. All IPN hydrogels show a fast deswelling rate and reversible swelling-shrinking property.