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哺乳动物细胞光电行为的机理研究
引用本文:张春阳,慈云祥.哺乳动物细胞光电行为的机理研究[J].高等学校化学学报,2000,21(3):354-357.
作者姓名:张春阳  慈云祥
作者单位:北京大学化学系, 北京 100871
基金项目:国家自然科学基金!(批准号 :39730 16 0 )
摘    要:研究了阿霉素、寡霉素和秋水仙素对细胞光电流的影响,发现细胞光电流的变化可适时表征药物对细胞的作用,且药物对细胞光电流的抑制率具有剂量和时间依赖性.据此提出了“光激励酶促反应加速模型”,并对哺乳动物细胞光电行为的机理进行了探讨.

关 键 词:哺乳动物细胞  光电行为  光电流  
收稿时间:1999-05-08

Theoretical Study on the Photoelectric Behavior of Mammalian Cells
ZHANG Chun-Yang,CI Yu-Xiang.Theoretical Study on the Photoelectric Behavior of Mammalian Cells[J].Chemical Research In Chinese Universities,2000,21(3):354-357.
Authors:ZHANG Chun-Yang  CI Yu-Xiang
Institution:Department of Chemistry, Peking University, Beijing 100871, China
Abstract:The effectiveness of doxorubicin, oligomycin and cholchicine on living cells was studied with the photoelectric method in this paper. The results indicated that the change of photoelectric current can reflect the effectiveness of drugs on living cells, and the inhibition effect of drugs on the photoelectric current of living cells was dependent on the drug concentration and drug-treating time. Based on these results, a model of “light-induced enzymatic-reaction acceleration” for the photoelectric behavior of mammalian cells had been proposed as well.
Keywords:Mammalian cell  Photoelectric behavior  Photoelectric current
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