基于金属卟啉的甲基磷酸二甲酯分子印迹聚合物微球的合成及性能

合成了分别以5-(4-甲基丙烯酰氧苯基)-10,15,20-三苯基锌卟啉(ZnMOTPP)和5-(4-甲基丙烯酰氧苯基)-10,15,20-三苯基钆卟啉(GdMOTPP)为功能单体, 甲基丙烯酸(MAA)为辅助功能单体的甲基磷酸二甲酯(DMMP)分子印迹聚合物微球. 扫描电子显微镜(SEM)表征结果表明, 微球平均粒径为50～100 μm, 粒度均匀. 与甲基丙烯酸作为功能单体的分子印迹聚合物微球的吸附性能和特异性进行对比发现, ZnMOTPP分子印迹微球的吸附性能优于 GdMOTPP分子印迹微球, 金属卟啉分子印迹微球的吸附性能优于仅以甲基丙烯酸作为功能单体的分子印迹微球, 并且微球对其印迹分子DMMP具有特异性吸附. Scatchard分析表明, DMMP分子印迹空穴中只存在一类结合位点, MIPMs-Zn+MAA的最大吸附量Q_max=148 μmol/g, MIPMs-Gd+MAA的Q_max=78.9 μmol/g, MIPMs-MAA的Q_max=13.57 μmol/g.

Synthesis and Properties of Molecularly Imprinted Polymeric Microspheres of Metalloporphyrins with Dimethyl Methylphosphonate as Template Molecule

Moleculary imprinted polymeric microspheres(MIPMs) based on 5-(4-methyl acryloyl oxygen phenyl)-10,15,20-triphenyl zinc porphyrin(ZnMOTPP) and 5-(4-methyl acryloyl oxygen phenyl)-10,15,20-triphenyl gadolinium porphyrin(GdMOTPP) were prepared with dimethyl methyl phosphonate(DMMP) as template and methacrylic acid(MAA) as auxiliary function monomer, including MIPMs-Zn+MAA, MIPMs-Gd+MAA and MIPMs-MAA. Scanning electron microscopy(SEM) images showed that the average particle size was between 50—100 μm and the particle size was uniform. Comparative study of adsorption and specificity showed that the adsorption capacity of MIPMs-Zn+MAA was superior to that of MIPMs-Gd+MAA. The adsorption capacities of MIPMs-Zn+MAA and MIPMs-Gd+MAA were much greater than that of MIPMs-MAA. MIPMs also showed better selectivity for DMMP through the isotherm binding test of diomethoate and phorate. By Scatchard analysis, the data of equilibrium adsorption experiment displayed that the MIPMs-DMMP only had one affinity binding site. The maximum absorption quantities of MIPMs-Zn+MAA, MIPMs-Gd+MAA and MIPMs-MAA were 148, 78.9 and 13.57 μmol/g, respectively.