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Two New Octahydronaphthalene Derivatives from Trichoderma spirale,an Endophytic Fungus Derived from Aquilaria sinensis
Authors:Dong‐Li Li  Yu‐Chan Chen  Mei‐Hua Tao  Hao‐Hua Li  Wei‐Min Zhang
Institution:1. State Key Laboratory of Applied Microbiology (Ministry‐Guangdong Province Jointly Breeding Base), South China, Guangdong Open Laboratory of Applied Microbiology, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, Guangzhou 510070, P.?R. China , (phone: +86‐20‐87137596 (D.‐L.?L.);2. +86‐20‐37656321 (W.‐M.?Z.);3. fax: +86‐20‐87688612;4. (D.‐L.?L.);5. (W.‐M.?Z.))
Abstract:Two new octahydronaphthalene derivatives, trichodermic acid A ( 1 ) and trichodermic acid B ( 2 ), along with a known analog, trichodermic acid ( 3 ), and a known modified dipeptide, trichodermamide A ( 4 ), were isolated from the extract of Trichoderma spirale, an endophytic fungus present in the medicinal plant Aquilaria sinensis. The structures of these compounds were established by extensive analysis of their spectroscopic data including 1D‐ and 2D‐NMR and MS data.
Keywords:Aquilaria sinensis  Trichoderma spirale  Trichodermic acids A and B  Fungi
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