Highly Conjugated Ergostane‐Type Steroids and Aranotin‐Type Diketopiperazines from the Fungus Aspergillus terreus BCC 4651 |
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| Authors: | Rachada Haritakun Pranee Rachtawee Somjit Komwijit Sutichai Nithithanasilp Masahiko Isaka |
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| Institution: | 1. National Center for Genetic Engineering and Biotechnology (BIOTEC), 113 Thailand Science Park, Phaholyothin Road, Klong Luang, Pathumthani 12120, Thailand, (phone: +66‐25646700 ext 3554;2. fax: +66‐25646707) |
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| Abstract: | Two new ergostane derivatives, 12β,15α,25,26‐tetrahydroxyergosta‐4,6,8(14),22‐tetraen‐3‐one ( 1 ) and 12β,15α,25,28‐tetrahydroxyergosta‐4,6,8(14),22‐tetraen‐3‐one ( 2 ), and a new aranotin‐type diketopiperazine, bisdethiobis(methylsulfanyl)apoaranotin ( 3 ), were isolated from the fungus Aspergillus terreus BCC 4651. The structures of the new compounds were elucidated by means of NMR spectroscopic and MS analyses. |
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| Keywords: | Aspergillus terreus Ergostane derivatives Aranotin derivatives Diketopiperazines Steroids Antimycobacterial activity |
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