Two New Triterpene Lactones from the Stems of Kadsura polysperma |
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| Authors: | Zhengwei Jia Yan Lu Zhixin Liao Daofeng Chen |
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| Institution: | 1. Department of Pharmacognosy, School of Pharmacy, Fudan University, Shanghai 200032, P.?R. China, (phone: +86‐21‐54237453;2. fax: +86‐21‐64170921) |
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| Abstract: | Two new triterpene lactones, polysperlactones A ( 2 ) and B ( 3 ), were isolated from the stems of Kadsura polysperma, together with the known compounds heteroclitalactone D ( 1 ) and schisanlactone E ( 4 ). Their structures were elucidated by spectroscopic methods, including 2D‐NMR and HR‐MS techniques. The configuration of 1 was confirmed by X‐ray analysis. Compounds 2 and 3 are members of a rare class of 3,4‐secolanostane metabolites with ring‐expanded or cyclized structures, respectively. |
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| Keywords: | Kadsura polysperma Triterpene lactones Polysperlactones A and B Lactones Heteroclitalactone D Schisanlactone E |
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