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Four New Lanostane Triterpenoids from Euphorbia humifusa
Authors:Zhi‐Qiang Lu  Guang‐Tong Chen  Jin‐Qiang Zhang  Hui‐Lian Huang  Shu‐Hong Guan  De‐An Guo
Institution:1. Shanghai Research Center for Modernization of Traditional Chinese Medicine, Shanghai Institute of Materia Medica, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Guo Shoujing Road 199, Zhangjiang, Shanghai 201203, P.?R. China, (phone: +86‐21‐50271516;2. fax: +86‐21‐50272789)
Abstract:Four new lanostane triterpenoids, namely (3β)‐3‐hydroxy‐24‐methylenelanost‐8‐ene‐7,11‐dione ( 1 ), (3β)‐3‐hydroxylanosta‐8,24‐diene‐7,11‐dione ( 2 ), (3β,7α)‐3,7‐dihydroxylanosta‐8,24‐dien‐11‐one ( 3 ), and (3β,11β)‐3,11‐dihydroxylanosta‐8,24‐dien‐7‐one ( 4 ) were isolated from Euphorbia humifusa, together with 2 known compounds. The structures of these new compounds were elucidated on the basis of extensive spectroscopic analysis and comparison with the related known compounds.
Keywords:Euphorbia humifusa  Lanostane triterpenoids  Triterpenoids
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