Phosphodiesterase‐Inhibiting Glycosides from Symplocos racemosa |
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| Authors: | Viqar&#x;Uddin Ahmad Muhammad&#x;Athar Abbasi Muhammad Zubair Naheed Fatima Umar Farooq M&#x;Iqbal Choudhary |
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| Institution: | Viqar Uddin Ahmad,Muhammad Athar Abbasi,Muhammad Zubair,Naheed Fatima,Umar Farooq,M. Iqbal Choudhary |
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| Abstract: | Phytochemical investigation of Symplocos racemosa resulted in the isolation of two new glycosides, symploracemoside ( 1 ) and symplomoside ( 2 ), which are structurally related to the reported benzoylsalireposide ( 3 ) and salireposide ( 4 ). The structure elucidation of the isolated compounds was based primarily on 1D‐ and 2D‐NMR analysis, including COSY, NOESY, HMQC, and HMBC correlations. These glycosides showed inhibitory activity against snake‐venom phosphodiesterase I. |
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