Synthese und Konfiguration einiger Spiro [indan-2,2′-pyrrolidin]- und Spiro [pyrrolidin-2,2′-tetralin]-Derivate,

Synthesis and configuration of some spiro indan-2,2′-pyrrolidine] and spiro pyrrolidine-2,2′-tetraline] derivatives Catalytic hydrogenation of the nitrosoindan and nitrosotetralin derivatives 8 yielded trans-1-hydroxy-spiro indan-2,2′-pyrrolidin]-5′-one ( 9 ) and trans-1′-hydroxy-spiro pyrrolidine-2,2′-tetralin]-5-one ( 10 ) respectively, whilst the corresponding cis compounds 12 and 15 were prepared via the chlorides 11 and 14 . The configurations of 10 and 13 were determined by X-Ray analysis.