Eight New Diterpenoids from the Roots of Euphorbia nematocypha |
| |
| Authors: | Fei He Jian‐Xin Pu Sheng‐Xiong Huang Wei‐Lie Xiao Li‐Bin Yang Xiao‐Nian Li Yong Zhao Jian Ding Cheng‐Hui Xu Han‐Dong Sun |
| |
| Institution: | 1. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650204, P.?R. China, (phone: +86‐871‐5223251;2. fax: +86‐871‐5216343);3. Graduate University of the Chinese Academy of Sciences, Beijing 10039, P.?R. China;4. Shanghai Institute of Materia Medica, Shanghai Institute for Biological Science, Chinese Academy of Sciences, Shanghai 201203, P.?R. China |
| |
| Abstract: | From the dried roots of Euphorbia nematocypha, eight new diterpenoids, with ent‐atisane (i.e., 1 – 5 ) and isopimarane (i.e., 6 – 8 ) type skeletons, together with five known compounds, were isolated. The structures of these new compounds were elucidated by spectroscopic data. Compounds 1 – 8 were evaluated for their cytotoxicity against a small panel of human cancer cell lines. |
| |
| Keywords: | Euphorbia nematocypha Diterpenoids Isopimaranes ent‐Atisanes |
|
|
