A tandem synthesis of 3-aroylcoumarinoflavones catalyzed by <Emphasis Type="SmallCaps">l</Emphasis>-proline and their antioxidant activity |
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| Authors: | G Thirupathi E Yadaiah Goud Y Hemasri MD Suban Ali Y Jayaprakash Rao |
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| Institution: | 1.Department of Chemistry,Osmania University,Hyderabad,India;2.Department of Chemistry,Telangana University,Nizamabad,India;3.Department of Chemistry, Nizam College,Osmania University,Hyderabad,India;4.Department of Biochemistry,Sri Venkateswara University,Tirupati,India |
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| Abstract: | A facile, convenient, efficient and high-yielding synthesis of 3-aroylcoumarinoflavones has been developed by the condensation of easily synthesized 7-hydroxy-8-formylflavones and benzoyl acetonitriles in the presence of catalytic amount of l-proline in ethanol reflux. All the synthesized compounds were evaluated for their antioxidant activity. Some of the compounds showed very good activity compared to standard BHT. |
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