Two new lactones and one new aryl-8-oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia sophia |
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| Authors: | Sun Kai Li Xian Li Wen Wang Jinhui Liu Jianming Sha Yi |
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| Institution: | Research Department of Natural Medicine, Shenyang Pharmaceutical University, Shayang, PR China. |
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| Abstract: | Two new lactones (1, 2), descurainolide A and B, and one new aryl-8-oxa-bicyclo3,2,1]-oct-3-en-2-one (3), descurainin, together with five known compounds (4-8), were isolated from the seeds of Descurainia sophia (L.) WEBB ex PRANTL. The structures of the new compounds were elucidated by extensive studies of their 1D, 2D NMR and HR-MS. Compounds 4 and 5 showed cytotoxicity. |
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