Synthesis and cellular effect of a novel conjugate of polyamide and phospholipid |
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| Authors: | Liu Yi Deng Yulin Zheng Rong Zhang Peilong Zhai Hui Zhu Changjin |
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| Institution: | Department of Applied Chemistry, Beijing Institute of Technology. |
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| Abstract: | In order to improve the cell penetration of polyamide and its movement toward nucleic DNA we synthesized a conjugate of polyamide and phospholipid, which showed a significantly reducecd cytotoxicity and effective apoptosis when comparing with the native polyamide. |
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