Enhanced Electrochemical Response of Isoniazid Electrocatalytic Oxidation on RGO-PPD-SiW Modified Electrode |
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| Authors: | E Yu Pisarevskaya A L Klyuev A V Shapagin O N Efimov |
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| Institution: | 1. A?N. Frumkin Institute of Physical Chemistry and Electrochemistry, Russian Academy of Sciences, 119071 Moscow, Russia;2. Federal Research Center of Problems of Chemical Physics and Medicine Chemistry, Russian Academy of Sciences, 142432 Chernogolovka, Russia |
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| Abstract: | The electroactive composites based on reduced graphene oxide (RGO), poly-o-phenylenediamine (PPD) and heteropolyacids – H4SiW12O40nH2O (SiW) and H3PW12O40] ? nH2O (PW) was applied to a screen-printed carbon electrode (SPCE) as a planar three-electrode cell as the first step to creating various devices, in particular, sensors and catalysts. We studied potential use of the modified and unmodified SPCE planar electrode in determining the concentration of antitubercular antibiotic isoniazid (isonicotinic acid hydrazide C6H7N3O or INH). The best result was observed for SPCE+RGO-PPD-SiW. CV of normal saline with various concentrations of C6H7N3O demonstrated linear dependence of the relevant anodic peak current either in the bulk solution upon immersion of the modified electrode or in a droplet on the electrode surface. |
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| Keywords: | poly-o-phenylenediamine silicotungstic acid reduced graphene oxide planar electrode isonicotinic acid hydrazide isoniazid |
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