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Dendritic Glycopolymer as Drug Delivery System for Proteasome Inhibitor Bortezomib in a Calcium Phosphate Bone Cement: First Steps Toward a Local Therapy of Osteolytic Bone Lesions
Authors:Christin Striegler  Matthias Schumacher  Christiane Effenberg  Martin Müller  Anja Seckinger  Reinhard Schnettler  Brigitte Voit  Dirk Hose  Michael Gelinsky  Dietmar Appelhans
Institution:1. Leibniz‐Institut für Polymerforschung Dresden e.V., 01069 Dresden, Germany;2. Organic Chemistry of Polymers, Technische Universit?t Dresden, 01062 Dresden, Germany;3. Centre for Translational Bone, Joint and Soft Tissue Research, Medical Faculty and University Hospital, Technische Universit?t Dresden, 01307 Dresden, Germany;4. Department of Internal Medicine V, Section Multiple Myeloma, Heidelberg University Hospital, 69120 Heidelberg, Germany;5. Laboratory for Experimental Trauma Surgery, Justus‐Liebig‐University Gie?en, 35392 Giessen, Germany
Abstract:
Keywords:calcium phosphate bone cement  dendritic glycopolymer  drug release  polyelectrolyte complex
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