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Guanidines as a nitrogen source for direct conversion of epoxides to aziridines |
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| Authors: | Tsuchiya Yukiko Kumamoto Takuya Ishikawa Tsutomu |
| Institution: | Graduate School of Pharmaceutical Sciences, Chiba University, 1-33 Yayoi, Inage, Chiba 263-8522, Japan. |
| Abstract: | Direct conversion of epoxides to aziridines was achieved with guanidines as a nitrogen source. Stereochemical inversion at the chiral centers of epoxides was observed without loss of optical purity. |
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