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Thermoheliox: effect on the functional hemodynamics of the human brain |
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| Authors: | Varfolomeev S D Panin A A Semenova N A Ublinskiy M V Akhadov T A Bykov V I Tsybenova S B |
| Institution: | 1.Institute of Physicochemical Foundations of the Functioning of Neural Network and Artificial Intellegence, Department of Chemistry, Moscow State University, Build. 11B, 1 Leninskie Gory, 119991, Moscow, Russian Federation ;2.N. M. Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, 4 ul. Kosygina, 119334, Moscow, Russian Federation ;3.MedTechInnovations, Limited Liability Company, 3-1 Blagoveshchenskii per., 123001, Moscow, Russian Federation ;4.Clinical and Research Institute of Emergency Pediatric Surgery and Trauma, Ministry of Health of the Russian Federation, 22 ul. Bol’shaya Polyanka, 119180, Moscow, Russian Federation ; |
| Abstract: | A kinetic study of the effect of thermoheliox (inhalation of a helium and oxygen mixture, 70 °C) on the functional hemodynamics of the human brain by functional magnetic resonance imaging was carried out. The dynamic responses of the BOLD signal were found to be biphasic. An empirical equation describing the first phase of the hemodynamic response to visual stimulus was proposed. It was shown that preliminary inhalation of thermoheliox stimulates the hemodynamic responses by slowing down the vasoconstriction. |
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