|
|||||
|
|
| Crystal Structure of 4—（4—chlorophenyl）—7,7—dimethyl—2,5—dioxo—1,2,3,4,5,6,7,8—octahydroquinoline | |
| 引用本文： | 屠树江,周建峰,等.Crystal Structure of 4—（4—chlorophenyl）—7,7—dimethyl—2,5—dioxo—1,2,3,4,5,6,7,8—octahydroquinoline[J].结构化学,2001,20(6):459-461. |
| 作者姓名： | 屠树江 周建峰 等 |
| 作者单位： | TU Shu-Jiang1* ZHOU Jian-Feng2 GAO Yuan3 LIU Xiao-Hong1 1(Department of Chemistry，Xuzhou Normal University，Xuzhou，Jiangsu 221009，China) 2(Department of Chemistry，Huaiyin Teacher College，Huaiyin，Jiangsu 223001，China) 3(Department of Chemistry，S |
| 基金项目： | Natural Science Foundation of Jiangsou Province. |
| 摘 要： | 1 INTRODUCTION Since the discovery of the pharmacological effects of 1,4-dihydropridines(1,4-DHPs) as calcium channel blocks1], a great deal of work has been directed towards synthesis of the novel 1,4-DHPs acting as calcium antagonists2, 3]. In fact, it is well-established that slightly modified structures on the DHP exhibit a calcium agents effect4, 5] ; however, two fused rings have been less well-studied. By refluxing equivalent amounts of dimedone, aromatic aldehyde Meldrum抯 … |
| 关 键 词： | 4－（4－氯苯基）－7 7－二甲基－2 5－二氧代－1 2 3 4 5 6 7 8－八氢喹啉 合成 晶体结构 |
Crystal Structure of 4-(4-chlorophenyl)-7,7-dimethyl-2,5- dioxo-1,2,3,4,5,6,7,8-octahydroquinoline |
|
| TU Shu-Jiang,LIU Xiao-Hong,ZHOU Jian-Feng,GAO Yuan.Crystal Structure of 4-(4-chlorophenyl)-7,7-dimethyl-2,5- dioxo-1,2,3,4,5,6,7,8-octahydroquinoline[J].Chinese Journal of Structural Chemistry,2001,20(6):459-461. | |
| Authors: | TU Shu-Jiang LIU Xiao-Hong ZHOU Jian-Feng GAO Yuan |
| Institution: | 1. Department of Chemistry, Xuzhou Normal University, 2. Department of Chemistry, Huaiyin Teacher College, 3. Department of Chemistry, Shenzhen University, |
| Abstract: | The crystal structure of the title compound (C17H18ClNO2) has been determined by single-crystal X-ray diffraction. The crystal is monoclinic with space group C2/c, a=23.677(5), b=9.5333(2), c=14.027(3)? b=98.06(3), V=313.5(1)?, Mr=303.77, Z=8, Dc=1.287g/cm3, l=0.71073, m(MoKa)=0.247mm-1, F(000)=1280. The structure was refined to R=0.0600, wR=0.1959 for 2020 reflections with I>2s(I). X-ray analysis reveals that the dihedral angle between plane 1 C(1)~C(6)] and plane 2 N(1), C(10), C(11), C(7)] is 78.8(1) , between plane 2 and plane 3 C(10), C(11), C(12), C(13), C(15)] is 3.95(7) . |
| Keywords: | quinoline synthesis crystal structure |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |