Multi-Residue Analysis of Some Polar Pesticides in Water Samples with SPE and LC–MS–MS

In the present study a multi-residue analytical method was developed for monitoring some polar pesticides such as acephate, methamidophos, carbofuran, isoproturon, dimethoate in water with SPE (solid-phase extraction) and LC–MS–MS. Acetochlor was taken as surrogate, and alachlor as internal standard. SPE with different types of columns was compared with LLE (liquid-liquid extraction). Further, the breakthrough volume for different pesticides was determined. The results showed that the selected pesticides can be determined very sensitively with LC–MS–MS. The minimum detectable quantity (MDQ) for each pesticide was about 1.0 ng. To date, SPE cartridge studies showed that the Oasis HLB cartridges were suitable for further studies. However, for Oasis HLB cartridge, different pesticide showed different breakthrough volume. The results showed that for acephate and methamidophos, the breakthrough volume was about 30 mL of water sample, much less than the breakthrough volume of other pesticides studied. Because of the higher vapor pressure and higher Henry's constant of methamidophos, dimethoate and carbofuran, much attention should be paid on their losses in the evaporation step of the experiment. This analytical method can be applied to determine pesticide contamination in environmental water samples. Revised: 12 September 2005 and 21 October 2005