Para-Fluorination of Anilides Using Electrochemically Generated Hypervalent Iodoarenes |
| |
| Authors: | Michael Berger Marola S Lenhard Prof?Dr Siegfried R Waldvogel |
| |
| Institution: | Department of Chemistry, Johannes Gutenberg University Mainz, Duesbergweg 10–14, 55128 Mainz, Germany |
| |
| Abstract: | The para-selective fluorination reaction of anilides using electrochemically generated hypervalent ArIF2 is reported, with Et3N ? 5HF serving as fluoride source and as supporting electrolyte. This electrochemical reaction is characterized by a simple set-up, easy scalability and affords a broad variety of fluorinated anilides from easily accessible anilides in good yields up to 86 %. |
| |
| Keywords: | anilides electrochemistry electrosynthesis fluorination hypervalent iodine |
|
